FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study

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FIRST: Fractional Flow Reserve and Intravascular Ultrasound Relationship Study.

OBJECTIVES FIRST (Fractional Flow Reserve and Intravascular Ultrasound Relationship Study) aimed to determine the optimal minimum lumen area (MLA) by intravascular ultrasound (IVUS) that correlates with fractional flow reserve (FFR) and to assess the correlation between virtual histology IVUS and FFR for intermediate coronary lesions. BACKGROUND FFR is considered the gold standard for assessi...

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F or several decades, bypass surgery has been regarded as the treatment of choice for patients with unprotected left main coronary artery (LMCA) disease. However, because of easy anatomic accessibility and a relatively large vessel caliber, left main percutaneous coronary intervention (PCI) for LMCA disease has become an attractive option for cardiologists. In addition, technical advances in PC...

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Validation of Intravascular Ultrasound-Derived Parameters With Fractional Flow Reserve for Assessment of Coronary Stenosis Severity

The authors assessed optimal intravascular ultrasound criteria for predicting functional significance of intermediate coronary lesions. Overall, 201 patients with 236 coronary lesions underwent intravascular ultrasound and invasive physiologic assessment preintervention. Fractional flow reserve (FFR) was measured at maximal hyperemia induced by intravenous adenosine infusion. FFR <0.80 at maxim...

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Validation of Intravascular Ultrasound-Derived Parameters With Fractional Flow Reserve for Assessment of Coronary Stenosis Severity

The authors assessed optimal intravascular ultrasound criteria for predicting functional significance of intermediate coronary lesions. Overall, 201 patients with 236 coronary lesions underwent intravascular ultrasound and invasive physiologic assessment preintervention. Fractional flow reserve (FFR) was measured at maximal hyperemia induced by intravenous adenosine infusion. FFR <0.80 at maxim...

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Validation of Intravascular Ultrasound-Derived Parameters With Fractional Flow Reserve for Assessment of Coronary Stenosis Severity

The authors assessed optimal intravascular ultrasound criteria for predicting functional significance of intermediate coronary lesions. Overall, 201 patients with 236 coronary lesions underwent intravascular ultrasound and invasive physiologic assessment preintervention. Fractional flow reserve (FFR) was measured at maximal hyperemia induced by intravenous adenosine infusion. FFR <0.80 at maxim...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2013

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2012.12.012